Helping People Achieve Clear Skin Since 2007

Helping People Achieve Clear Skin Since 2007

What Excess Iron Does To Your Skin And Acne

By Dr. Jaggi Rao, MD, FRCPC, Double board-certified dermatologist

For a long time, people were worried about getting too little iron in their diet, and with good reason. Before the developed world was flooded with abundance, iron deficiency was a real problem, resulting in iron-deficiency anemia and low hemoglobin, resulting in low red blood cell count. But in today’s modern world, developed societies rarely face this problem, aside from the vegan/vegetarian population. In fact, excess iron is a bigger issue and is more likely something that first-world citizens are dealing with, whether or not they’ve been diagnosed by a doctor.

As it turns out, excess iron, or iron overload, 💥🧲 is a real problem that causes damaging effects on the body, including making your skin and acne much worse.

Iron is what helps produce hemoglobin, which carries oxygen to your red blood cells.

Wait, Is Iron Good For You Or Bad For You?

First of all, iron is something that your body absolutely needs to survive. In that sense, it’s very good for you. Iron is what helps produce hemoglobin, which carries oxygen to your red blood cells. Without sufficient hemoglobin, you won’t have an efficient number of red blood cells in your body, resulting in weaker muscles and organs.

Iron isn’t just for helping transport oxygen throughout your body and blood, but is also necessary for growth, electron transport and the synthesis of DNA. 🧬 However, our bodies need iron in the right amounts. Having too much iron in your body, an excess of iron, results in a host of problems that are just as severe and life-threatening as having too little iron.

Iron is essential to our survival, but as it turns out, harmful pathogens also need iron to survive.

If we have too much iron in our system, these harmful pathogens also have excess iron and their numbers can grow until they generate infections. Iron also forms free radicals in our blood that can damage bodily tissues in our organs and even cause cancer. One way our bodies deal with iron is to lock it in our hemoglobin and ferritin, 🔒 which is something like a “cage” for the iron. Unfortunately, this isn’t always enough to limit the excess iron from being a problem in the body.

What Does The Body Do With Excess Iron?

Due to modern dietary modifications in the way we produce and supply food, the possibility of consuming and absorbing too much iron is really high. Supplemental iron, iron fortifications in food, toxins in food and the environment, oral birth control and even stress all contribute to the body’s ability to be exposed to iron overload. This is especially true for men, but even women are affected by it – even though their bodies have a natural mechanism for dumping excess iron – menstruation.

In fact, women actually absorb 3 times more iron than men due to their naturally higher estrogen levels, which boosts their ability to absorb iron from the foods they eat. 🥗🍗 That’s why shortening or stopping menstruation altogether can place women at severe risk of iron overload. Men, on the other hand, don’t menstruate and so they start to accumulate iron in the body from the time their puberty-related growth ends, which is usually anywhere from 18-21 years of age.

One obvious sign of iron accumulation, especially in men, is in their growing guts, or “beer bellies.” Often associated with the consumption of alcohol and beer, a beer belly is caused by boosted iron absorption – which alcohol actually helps the body to do. In fact, excess iron can cause obesity as the accumulation of iron leads to blood sugar problems, insulin resistance, and metabolic dysregulation.

One way the body tries to manage this excess iron is to deposit it into the different tissues in your various organs, such as the liver, pancreas, muscles, brain, adipose tissue, eyes, etc. 💪👀 But this leads to all kinds of diseases that degenerate bodily functions. Some of these diseases are heart disease, diabetes, Alzheimer’s, Parkinson’s, cancer and even Down syndrome in newborns.

It is also believed that iron overload progressed over time causes aging in the body. Age spots, for instance, are made of a fatty brown mass call lipofuscin, which is iron and oxidized polyunsaturated fatty acid (PUFA). People who have a lot of age spots also have a lot of excess iron in their bodies. This is because the excess iron gets deposited in the skin as the body runs out of other places to store the iron.

How Excess Iron Leads To Acne

Now that you understand what your body does to try and get rid of excess iron, it should start to become clear why excess iron can create problems for your skin! In fact, there are several ways that iron affects your body internally that result in skin issues, mainly acne.

  1. 📌 As mentioned in the last section, iron oxidizes the PUFA in your body which creates something called lipid peroxides. This further breaks down to form toxic compounds in your body that damages the tissues in your body and appears as damage, spots and blemishes on your skin (as well as in your other organs).
  2. 📌 Iron overload messes up your balance of gut flora as pathogens use iron to thrive and multiply. This allows the bad bacteria, like E. coli, Salmonella, Shigella, and C. diff to overpopulate your system and cause gut inflammation. Furthermore, as these pathogens weaken your guts mucosal membrane with the toxin they form, known as lipopolysaccharide or LPS, it causes leaky gut. This is where the pathogens and particles from food “leak” into your bloodstream and cause inflammation and other problems elsewhere in the body. When your digestive system gets really messed up, it affects your other organs and finally your skin, resulting in acne and other conditions like eczema and psoriasis.
  3. 📌 Excess iron leads to insulin resistance, where your body cannot metabolize insulin effectively, making it difficult for your body to digest carbs the way it should. This could lead to diabetes. But insulin resistance alone leads to skin problems. This is because when your body is resistant to insulin and you eat carbs and sugar-foods, your blood sugar levels and insulin spike. The excess insulin in your system stimulates excess sebum and skin cell production. This means the risk of your pores becoming clogged increases and likely will result in acne. Furthermore, insulin in the body stimulates inflammation in the skin, leaving your skin to become swollen and red.
  4. 📌 Your body tries to get rid of the excess iron in your body by storing it in your liver as a means of protecting your other vital organs, such as your heart and pancreas, from iron damage. But eventually, your liver runs out of space and also suffers damage from the iron overload. After all, iron creates free radicals and those cause oxidative damage. As a result, your liver’s ability to function becomes impaired, and that affects how it filters toxins, heavy metals, ingested pesticides, and other undesirable particles out of the body. When your liver can’t filter these toxins out, your body becomes overloaded with toxins and this triggers acne as the toxins find their way to your skin.
  5. 📌 Another key way that excess iron causes acne is by feeding the fungi in your body known as Candida. Candida is a yeast that is naturally occurring in the body, but an overgrowth of it can cause problems in the skin and inhibit the immune system from functioning properly. Acne caused by candida is not uncommon, and excess iron is exactly what the fungi need to fuel the overgrowth of its population.

These 5 ways that iron causes acne are just the most obvious ways that iron overload is problematic for your skin. But due to the host of problems that are associated with hemochromatosis (iron overload), there are possibly many other ways that iron results in the formation and perpetuation of acne.

Ways That Your Body May Be At Risk Of Iron Overload

Now that you understand the dangers and risks that iron overload poses to your skin and overall health, the next important thing to explore is how your body may be at risk. ✔️ As mentioned earlier, modern society has made the possibility of excess iron absorption ever-abundant, but in order to take charge of your health and skincare, you should know the specifics.

Too Much Red Meat

One of the most popular known sources of iron is the availability of red meat in the developed world, which is truly excessive. We can get it in many fast food restaurants or fine-dining establishments in the form of ground beef and steaks, known as “muscle meat”.

Red meat is mainly an American favorite, but it’s one of the main ways that we can consume too much iron.

That’s because these red meats have plenty of bioavailable heme iron, which means that it is very easy for the body to metabolize and absorb.

Traditionally, and in many parts of the world, when a cow is cooked, 🍖🔥 all of its parts are used in one form or another. This means that instead of slicing out only the juiciest, meat-only slabs of muscle, a lot of bone-in cuts are used, and bone marrow and bone broths are used in cooking. This allows for meals to be infused with calcium, and calcium counteracts iron absorption by inhibiting it. But in meals that don’t include these extras, it is likely that they are infused with an overdose of iron.

Lack Of Iron Antagonists

Speaking of calcium, one way to limit the amount of iron your body absorbs is to consume iron antagonists with your meal. But if your meals aren’t well-rounded, they might be lacking in sufficient iron antagonists, which will lead to excess iron absorption. Iron antagonists are things like raw dairy, turmeric, bitter herbs, teas (green, black, white), dark purple vegetables and other calcium-rich veggies, cocoa, cranberries, red wine, and, as previously mentioned, bone marrow and bone broth.

While traditional French cuisine features a lot of these ingredients in combination with their red meat meals, American cultures often don’t, which could be a leading reason why Americans face a much higher rate of modern diseases.

Not Using Raw Dairy

When it comes to the dairy products we use, most of them are pasteurized instead of raw dairy. This is due to the mass production of commercial dairy products manufactured for the general population. The pasteurization process involves heating the milk up to rid it of all the bacteria, but as a result, all the good stuff in the milk is processed out as well, including the elements that would counteract iron absorption. Even though raw milk is a healthier option for your digestive health, especially when eating it with iron-fortified cereals, it isn’t as mass-produced or widely available as pasteurized milk.

Iron Fortified Refined Flour

Iron-fortified grains and flours are very common in countries around the world, and some even require it. This could be because of the fact that refined wheat flour ends up with reduced iron, so iron is then deliberately added back into the mix. However, this type of iron is very easy for the body to absorb, and as a result, it’s a sure-fire way to end up with an easy excess of iron in the body. This includes foods like bread, cereals, crackers, cakes, cookies, pasta, etc. 🍞🥣🍪🧁🍝 In some countries, even the rice is iron-fortified. The best way to get around this is to use non-fortified whole wheat flour, and consume products made with that instead.

Fluoride

Fluoride is an ingredient that has become all too common in the known world, found in drinking water, toothpaste, dental treatments, pesticides, Teflon pans and more. It breaks down vitamin A in the body, which leads to ceruloplasmin deficiency. Ceruloplasmin is a copper-binding protein that your body creates using vitamin A. This protein helps to load iron into transferrin so that the iron can do what it’s supposed to do in your body, help get oxygen to your red blood cells. Without vitamin A, this process is inhibited and you end up with excess iron that isn’t going where it’s supposed to. As a result, the excess iron lingers in your liver and leads to all sorts of damage, as mentioned earlier.

Lack Of Vitamin A In Food

Vitamin A is a crucial component in making sure your body uses its iron intake properly. Aside from ingesting fluoride, which destroys it, a diet lacking sufficient vitamin A will also contribute to vitamin A deficiency. Vitamin A can be found in food like oranges and dark green veggies, 🍊🌿🍳🧀 and in animal food like egg yolk, grass-fed dairy, and liver.

Lack Of Molybdenum

An important mineral that is required to limit iron in the body is molybdenum. It helps to prevent the buildup of iron in your liver by getting it mobilized so it ends up in your hemoglobin. Naturally, without sufficient molybdenum, iron doesn’t get used as it should and it just builds up in your liver instead, to levels that literally become toxic.

The best way to avoid molybdenum deficiency and get enough of this mineral in your diet is from lentils and beans.

One way to know if you do have a molybdenum deficiency is if you get headaches from red wine and other food that has sulfites. Molybdenum is also necessary for the enzyme that is responsible for breaking down sulfites. Without it, you’ll experience what is known as sulfite intolerance.

Lack Of Copper And Zinc

Other deficiencies that could lead to excess iron in the body are copper deficiency and zinc deficiency. ⚡ Copper deficiency puts your body at risk of iron overload because your body also requires copper to get iron into transferrin, just like vitamin A. The lack of copper and zinc also contribute to iron overload due to the fact that these metals actually compete with iron to be absorbed. A sufficient amount of each limits the amount of iron your body can absorb, but a lack of them leaves a lot of room for the body to absorb iron in their place.

One of the reasons why copper and zinc are lacking in modern diets is because of modern farming practices. These days, modern soils are lacking in these two metals because the soil is over-farmed and strip-mined, without having the trace minerals replaced in any way. As a result, the crops that grow in these soils don’t have much copper and zinc to absorb. However, the soil is still very rich in iron, leading to crops that are infused with it.

Polycystic Ovary Syndrome (PCOS)

Women who have PCOS are more likely to have issues with iron overload. Some believe that this may be due to the increase in insulin levels in PCOS caused by insulin resistance. As described previously, insulin resistance enhances the body’s ability to absorb iron from food. Also, during PCOS, the hormone that helps to inhibit iron absorption, hepcidin, drops to much lower levels. 📉 As the level of this hormone drops in the body, the ability to absorb more iron increases.

Birth Control

As you read earlier, the female body has a way of dumping excess iron every month through menstruation. Birth control, however, is designed to limit and, in some cases, even halt menstruation altogether. 🩸 This causes the body to accumulate the iron it should be dumping, leading to an excess. This can be a huge problem for women, as women are already able to absorb three times as much iron as men from the food they eat.

In fact, one of the main reasons why women experience acne after stopping birth control is due to the accumulated excess iron that has been stored away in their bodies during the time they were on birth control. Even though they may not have experienced acne during the time they were taking birth control – due to progesterone which gives you clear skin – stopping their progesterone intake allows the iron to surface and wreak havoc on their skin. That’s why women on birth control need to be very careful of their iron intake during that period of their lives.

How To Deal With Excess Iron

There are a few ways to test for iron levels in your body, such as liver biopsies, MRIs, ferritin level tests, transferrin saturation tests, iron levels tests for hair and gamma-glutamyl transferase tests. ⚕️ If you do see a doctor or send samples into a lab for testing and find out that you have excess iron, your next step is to begin finding ways to reduce the iron levels in your body.

Eat Foods That Inhibit Iron

This is probably the most obvious solution to an iron excess problem. Your diet should include foods that inhibit your body’s ability to absorb too much iron. That means that when you have a red meat meal, for example, you should have it with a glass of red wine, some bone broth or even black, green or white tea. 🥩🍷🍵 Whenever you consume flour-based foods that contain fortified iron, you should pair it with tea, eggs, cocoa, turmeric, cranberries, calcium-rich vegetables or other iron antagonists.

Keep in mind that your diet should include a daily dose of vitamin A, copper, zinc and molybdenum, as mentioned earlier. If you are interested in tasty food pairings that work together well and supply your body with everything it needs, look no further than ethnic cuisine ideas from around the world, which you can easily do online.

Remember, French cuisine is an ideal example of meal combinations that have good pairings of iron-rich and iron-antagonist foods.

Take Iron Chelators

Similar to iron-antagonists, or iron-inhibitors, iron chelators are another way to deal with excess iron. Iron chelators bind themselves to iron and take it where it needs to go in the body. In the case of excess iron, chelators escort it out of the body. The most natural form of this is called inositol hexaphosphate, or IP-6. It’s a phytic acid that has been isolated from rice bran and can actually effectively kill cancer cells. That’s probably due to the fact that it removes excess iron from the body, and excess iron is needed for cancerous cells to feed on and multiply.

The only real problem with it is that IP-6 is also a chelating agent for copper, magnesium, zinc and other important minerals that your body really needs. That’s why it should be taken separately from your meals. One way to do it is half an hour to an hour before you eat breakfast in the morning. 🍽️🌞 The goal here is to make sure it doesn’t wipe away these other precious minerals from your diet, but instead only deals with the excess iron already in your body.

Another reliable iron chelator is lactoferrin, a protein that the human body naturally produces in all of its secretions. But drinking bodily fluids is a gross way to get your lactoferrin intake. That’s why there are lactoferrin supplements that you can take. Additionally, you can get lactoferrin from raw milk, but you would only get it in small portions. Supplements are probably the best way to get a proper dose of it.

Finally, perhaps a surprising fact is that some antibiotics, mainly the tetracycline family of antibiotics, are strong iron chelators as well. 💊 If you happen to be prescribed these antibiotics for a short while, they will be able to assist your body in lowering your iron levels. However, as antibiotics are designed to kill bacteria in the body, they can adversely affect your gut flora and an unhealthy gut will cause acne anyway, so antibiotics need to be taken with extreme caution.

Avoid Iron-Fortified Foods

The next obvious way to cut down on excess iron is to stop eating foods that are iron-fortified. ✂️ This means cutting out the wrong breakfast cereals, white bread, pastas, and generally anything made from refined white flour.

Cut Down On Your Meats

You’ve already read that red meats are very high in iron and can lead to excess iron very quickly. The reality is that your body doesn’t need to have meat every single day of the week to be healthy, and in fact, having meat daily with each meal can really be too much. One sure-fire way to cut down on excess iron, therefore, is to cut down on your meat intake. Studies have shown that vegetarians tend to have lower iron levels and more sensitivity to insulin, so their bodies break down carbs very well in comparison to intensive meat-eaters.

While this does not mean that you should turn vegetarian yourself, it does mean that you should up your veggie intake and reduce your meat intake quite a bit.

Instead of red meats, you can opt for seafood, which has the necessary animal proteins that your muscles require.

Seafood also has more minerals like copper and zinc than red meat has. Whenever you do decide to eat red meat, be sure to pair it with an iron antagonist.

Cut Down On Sugar

As you already know, sugar spikes blood sugar and insulin levels, and that can lead to insulin resistance and excess production of sebum and skin cells. It also causes your body to produce less hepcidin, the hormone that stunts iron absorption, in turn boosting how much iron your body absorbs. Carbs are sugars so food made with iron-fortified flours combined with sugar, like cookies and cakes, are just sugar on sugar and a recipe for iron overload. The best way to deal with that is to cut out as much sugar from your diet as possible, no matter how much you might love it.

Eat Beans Regularly

One of the best ways to stop iron from building up in your liver is to have enough molybdenum in your system, and the best way in the world to do that is to eat beans regularly, even daily. 📅 This trace mineral keeps iron mobilized in your body so it doesn’t get piled up in your liver, but rather gets put to use in your hemoglobin. That’s probably also the reason why studies have shown that people who eat beans regularly have cleaner intestines and digestive systems than people who don’t!

Get Enough Vitamin C

Now, this one may be a bit controversial, as some doctors would strongly recommend that having supplemental vitamin C is a recipe for disaster when you’re already dealing with iron overload. So, let’s first clarify why vitamin C matters and how it relates to iron.

💡 Vitamin C is necessary for your body to be able to use the iron it absorbs from your food. Without a sufficient amount of vitamin C, your body can’t really use the iron it absorbs so it ends up just building up in your liver while you become anemic (low on red blood cells). Vitamin C does boost iron absorption but there is only so much vitamin C your body can actually absorb in a given period of time, so the effects are limited in your overall diet.

Vitamin C is actually needed for iron to be properly utilized in the body, and it even protects your body from iron toxicity.

Without it, your body will undergo both iron overload and anemia at the same time, as weird as that may sound. 🩺 Even though some doctors caution against high vitamin C intake for fear of increasing iron absorption, vitamin C by itself cannot actually cause iron overload in your body. In fact, as with molybdenum, it helps to mobilize it and get it moving in your body instead of sitting in your liver and building up.

A safe amount of vitamin C to take is about 2000 mg and you can increase it slowly from there. You know you’re having too much if it gives you diarrhea. Also, you should take it in doses spread out over the course of the day, so two or three times. This is because vitamin C will only remain present in your body for a short amount of time before your body metabolizes it.

Holistic Therapy

Finally, a less conventional and perhaps harder to come by method of dealing with iron overload is a holistic method known as near-infrared sauna therapy. It is essentially sitting in an infrared sauna to trigger your body’s ability to get rid of iron through sweating and releasing it into your hair. 🧖🏻‍♀️🧖🏼‍♂️🧖🏽‍♀️🧖🏾‍♂️🧖🏿‍♀️ If you are fortunate enough to find a spa or clinic that offers this type of treatment, you should do it. It is an excellent way to have your body naturally dump out its excess iron without having to consume anything extra.

The Bottom Line

✅ The key takeaway here is that iron, though absolutely necessary for your body to work properly, can be very toxic and harmful to your skin and health when you have an excess.

Iron overload causes acne in several ways, and there are many ways that we put ourselves at risk of iron overload on a daily basis. Fortunately, there are ways to cut down on your iron intake and to even get rid of some of the excess iron in your body. These methods include consuming iron chelators, iron-antagonists and vitamins and minerals that help to mobilize and transport iron to where it needs to be in the body to be beneficial.

If you make healthy choices 👍🏻👍🏼👍🏽👍🏾👍🏿 combined with sensible efforts to reduce your existing iron overload, you should see results that will not only give you better skin, but give you better overall health as well.

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Charles Reply

I guess this explains my undying love for beans and oranges...

March 2, 2019 at 5:32 am Reply